I am very particular about my audio... my home set up is rather nice (McIntosh, B&W, etc).
Here are the settings that work the best for me. It definitely tames the high end/treble and keeps the bass from being boomy. With these settings, you should be able to turn it up with your ears bleeding, or experiencing too much distortion from the bass frequencies.
Interestingly, my settings aren't too far off from member Sirrus